Using state-of-the art ocean and atmospheric modelling, available in-situ and remote sensing observations and global reanalyses, we are working on modeling and studying all aspects of the Red Sea circulation, dynamics, climate, and their impact on the ecosystems productivity. As part of this work, we have generated the highest resolution ocean and atmospheric reanalyses for the region. These 40-year reanalyses are currently being used to study the dynamics of the region and its response to changes in the global climate, and also to support many governmental and industrial projects that are being developed along the shores of the Red Sea. The project is producing an unprecedented knowledge of the oceanic and atmospheric circulations of the region, their long-term alterations, and the potential impact of these on the ecosystem and their interactions with the regional weather and climate.